Яндекс Метрика
Биология и ИИ

ESM2-8M

Meta AI,New York University (NYU),Stanford University,Massachusetts Institute of Technology (MIT)
ProteinsProtein or nucleotide language model (pLM/nLM)Protein folding prediction

Самая легкая модель в линейке ESM2, идеально подходящая для оперативной обработки данных и ресурсоэффективных задач. Этот ИИ-инструмент сохраняет высокую точность в работе с последовательностями, делая современные технологии анализа белков доступнее.

"Recent advances in machine learning have leveraged evolutionary information in multiple sequence alignments to predict protein structure. We demonstrate direct inference of full atomic-level protein structure from primary sequence using a large language model. As language models of protein sequences are scaled up to 15 billion parameters, an atomic-resolution picture of protein structure emerges in the learned representations. This results in an order-of-magnitude acceleration of high-resolution structure prediction, which enables large-scale structural characterization of metagenomic proteins. We apply this capability to construct the ESM Metagenomic Atlas by predicting structures for >617 million metagenomic protein sequences, including >225 million that are predicted with high confidence, which gives a view into the vast breadth and diversity of natural proteins."

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